SNPs in the coding region of Hsp70 gene could affect peptide-binding kinetics or affinity of the Hsp70 proteins and ATPase activity, while nucleotide changes in the flanking regions (promoter and 5′, 3′-UTR) might affect inducibility, degree of expression or stability of Hsp70-mRNA (Lamb et al. 2007). In farm animals, some studies reported possible associations of SSCP patters due to the identified SNPs among the allelic variants of the Hsp70 genes with stress response and tolerance to heat (Bhat et al. 2016).