Dear Jinan Sadeq

Pls. find the attached files

Hoping this will be helpful

Regards

Prof. Houda Kawas

http://onlinelibrary.wiley.com/doi/10.1002/ana.410340420/full

http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0714.2007.00586.x/full

http://www.nytimes.com/health/guides/disease/herpes-simplex/possible-complications.html

https://www.ncbi.nlm.nih.gov/pubmed/18474734

http://www.who.int/mediacentre/factsheets/fs400/en/

http://emedicine.medscape.com/article/218580-overview

http://jamanetwork.com/journals/jamaneurology/fullarticle/795486

https://medlineplus.gov/ency/article/000606.htm

http://www.webmd.com/genital-herpes/tc/other-health-problems-caused-by-herpes-simplex-virus-topic-overview

Also

http://www.aafp.org/afp/2002/0315/p1138.html

http://www.sciencedirect.com/science/article/pii/S1083879109003000?np=y&npKey=bbe08fbdad3a749d2823f3deade81994af8db928cd660afce769351424e1d0e8

https://patient.info/doctor/oral-herpes-simplex

http://umm.edu/health/medical/reports/articles/herpes-simplex

http://www.healthline.com/health/herpes-simplex?m=0

http://www.mayoclinic.org/diseases-conditions/cold-sore/basics/complications/con-20021310

http://www.merckmanuals.com/home/infections/viral-infections/herpes-simplex-virus-infections

https://www.stdcheck.com/herpes-1-risks-complications.php

And

Hoping this will be helpful to your project

http://emedicine.medscape.com/article/218580-clinical

http://www.nejm.org/doi/full/10.1056/nejm199911043411904

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129463/

http://www.sciencedirect.com/science/article/pii/S1083879109003000

hi

Article Signal transducer and activator of transcription 3 (Stat3) r...

https://patient.info/doctor/oral-herpes-simplex

Dear jinan

The severity of symptoms depends on where and how the virus enters the body. Except in very rare instances and in special circumstances, the disease is not life threatening, although it can be very debilitating and cause great emotional distress.

Herpes simplex in any patient with a seriously compromised immune system can cause serious and even life-threatening complications, including:

Pneumonia

Inflammation of the esophagus

Encephalitis (inflammation of the brain)

Destruction of the adrenal glands

Disseminated herpes (spread of infection throughout the body)

Liver damage, including hepatitis

OTHER COMPLICATIONS

Urinary retention . Urinary retention in women, especially with the first outbreak, is not uncommon. Some women need to use an indwelling catheter for a few days to a week.

thank you so much Dr Jameela good answer

It seems clear good cooperation with participants and colleagues in the same place, good luck

hi dear https://www.researchgate.net/topic/HSV-1

Hi

I agree with Dr. Huda kawas

regards