I think you need to provide more information regarding your question.
In power plant there is two categories for calculation of water consumption. one will be there for Steam generation and second will be there for cooling.
both the circuits have losses as per process conditions and parameters we will be maintaining.
On over all at big power plant for steam generation water requirement is 3TPH/MW with 5% losses. and cooling water calculation will be based on heat load, which is roughly 80 times of water required to generate the steam. So water consumption in steam generation will again varied based on type of turbine (back pressure or condensate) and inlet steam enthalpy (Pressure and temperature), because each degree raise in steam temperature, pressure and volume of steam will vary and will vary the water consumption.
for cooling water loop based on turbine design (back pressure or condensate) heat load on condenser will vary and that will decide the heat load and cooling water requirement, with that most of cooling tower will work in range of 65-75 % efficiency in heat rejection, with that 10-20 % losses to be considered.
I Hope it might have provided some help in go ahead further, so in case you can some up with basic details it can be calculated precisely.
For example, in (Macknick et al., 2012) we can find operational water consumption and withdrawal factors for electricity generating technologies, so basically my question was focused on finding water coefficients (both consumption and withdrawals) when producing electricity for power plants with the features mentioned above (circulating fluidized bed technology and open-loop cooling system).
The water consumption in power plants, based on operational experince, is generally considered 4% of thermal cycle circulating water ( This figure is reffered to demineralized water consumption and not covered general service and potable water uses) .