Does World Hemophilia Federation recommended any management plans OF covid 19 in patients of bleeding disorders? As they mostly are immunodeficient already.
Thanks for sharing this useful discussion, I hope the following link will helpful
COVID-19 vaccination guidance for people with bleeding disorders – Hemophilia World News
https://news.wfh.org/covid-19-vaccination-guidance-for-people-with-bleeding-disorders/
Sufficient information in the link offered by dr. Ekhlas A Hussien.
I would recommend elective endotracheal intubation to protect health care workers from infection and enable respiratory support as needed. I would manage patients with generous narcotic dosage, permissive hypercarbia, and minimal sedation as essential to prevent agitation. Hypercarbia optimizes oxygen transport and delivery, which prevents and mitigates sickle cell crisis. Narcotic analgesia mitigates pain and sympathetic nervous activity that closes the capillary gate and aggravates tissue hypoxia and painful lactic acidosis. Hypercarbia counteracts the respiratory depression of narcotics. I would take measures to prevent hypothermia. I would maintain red cell mass within normal limits to prevent excessive blood turbulence caused by anemia and avoid hyper coagulability caused by polycythemia. These measures should minimize the body's stress reaction caused by the virus and optimize recovery. In the absence of bleeding problems I would recommend treatment with MgSO4 using eclampsia treatment protocols to prevent stress mechanism hyperactivity and optimize recovery from the virus.
https://www.medscape.com/answers/779322-197558/what-are-the-world-federation-of-hemophilia-wfh-recommendations-for-the-management-of-covid-19-in-patients-with-hemophilia-a
https://hemaware.org/mind-body/managing-bleeding-disorder-during-pandemic-answers-6-common-questions-about-covid-19
Patients with bleeding disorders, when get infected with COVID 19 :
1,The anticoagulant protocol is similar but they will require a prophylactic doses of factors replacement that they are sufferering from.
2. The drug like amecizumab can be continued with more vigilance required for coagulation.
3. Vaccine schedules are same but some patients may require prophylactic factors replacement.
