First, N-Acetylcystiene is not Anti-mucolytic. Rather it is Mucolytic. Which means it helps to reduce the density and thickness of mucus produced in the lungs and consequent helps you cough them out. This the same class with Expectorants. Generally, it is a drug still being understood owning to its very many capabilities from Respiratory, dermatological, hepatotoxicity control in Acetaminophen poisoning etc.. however, i think the most important fact is that N-acetyl cysteine (NAC) is used by the body to build antioxidants. Antioxidants are vitamins, minerals, and other nutrients that protect and repair cells from damage. Also, with the knowledge that Acetylcysteine is a derivative of the natural amino acid cysteine, which serves as a substrate for the synthesis of glutathione (GSH) which is mainly how it helps detoxify in Acetaminophen poisoning.

In this question, you didn't mention stage of COVID-19 so I am assuming in Mild Cases where none productive cough is a symptom.. and then yes.. n Acetylcysteine can be used to help the cough to get productive and decongest the lungs.. i think it is reasonable..

Doctor @Idowu Goodnews Oluwaseyi

Thank you very much for your correction and your scientific reply.

For the stage of treatment I think it is used for productive cough when there is difficult breathing with sputum as I hear from a doctor in UAE who is treating covid19 patients clinically..

Best regards.

Please see the following RG link:

Article N-acetylcysteine as a potential treatment for novel coronavi...

All mucolytics reviewed have a good safety profile, although some precautions should be taken when using ambroxol and bromhexine, and the use of NAC and carbocysteine should be monitored in special patient groups. Overall, however, the available evidence from randomised, controlled, and observational trials, as well as pragmatic, real-life experience, suggests that these products are useful in the therapy of upper respiratory airways infections, including bronchitis, sinusitis, and rhinosinusitis.

Doctor @Manal Hadi Kanaan

I have requested the paper

Thank you very much

Doctor @Omer Mohi U Din Sofi

Thank you very much.

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