What are the problems of using water with pyridinium chlorochromate in oxidation reactions ?

Sahar ibrahim abu-turki @Sahar-Abu-Turki

29 January 2018 1 5K Report

usually , PCC is used with dichloromethane as solvent , and water does not used , Why ? especially with carponyl compounds .

Salim Y Hanna

Hi Sahar,

PCC is mild oxidizing agent commonly used as oxidizing agent it will oxidize primary alcohol to aldehyde and secondary to ketone .If you used PCC with water,the PCC will convert to H2CrO3, which has no ability for oxidation. Good luck.

Badges
Science topic

Similar topics
Chemistry
Chemicals
Solvents

More Sahar ibrahim abu-turki's questions See All

E.coli contamination in human RNA seq data ?

Recently, we observed that 99% of the sequences in our RNA-seq data corresponded to the E. coli genome. Despite multiple DNAse treatments after RNA extraction and ribosomal depletion, we were...

06 August 2024 807 3 View

How Social Media Affects Your Mental Health ?

How Social Media Affects Your Mental Health

04 August 2024 6,961 3 View

Do You Know Untreated TMJ Affects Your Brain And Entire Body?

04 August 2024 6,282 1 View

What Are the Main Reasons for Publications?

23 June 2024 3,199 1 View

How to Calculate the Sample Size in an Analytical Study?

23 June 2024 3,375 3 View

What Should the Sample Size Be for a Research Study?

23 June 2024 2,942 3 View

Is Publication in Medical Journals a New Phenomenon?

23 June 2024 9,070 1 View

How Can a Clinician Take Out Time from His/Her Schedule for Publication?

23 June 2024 526 1 View

How Can I Determine Sample Sizes for Diagnostic Test Studies?

23 June 2024 3,612 5 View

What Are the Various Types of Clinical Study Designs?

23 June 2024 1,494 4 View

What is the solvent for 8YSZ nano material?

I need to do some experiment with it in liquid form.

07 August 2024 613 3 View

Which solvent is better to dissolve with secondary metabolites extracted from fungi?

I work on MCF7 cell cell for anticaner purpose and I wa to do drug preperation the drug ( secondary metabolites extracted from Aspergillus) My question which solvent is better with these secodary...

03 August 2024 4,725 2 View

I need to dissolve stigmasterol for an animal experiment, it hasn't dissolved in either DMSO or vegetable oil. Can anyone recommend the best solvent?

Hello everyone, I need to dissolve stigmasterol for an animal experiment, but it hasn't dissolved in either DMSO or vegetable oil. Can anyone recommend the best solvent for stigmasterol?

01 August 2024 7,504 2 View

Why methanol and sulphuric acid used in the analysis of polyhydroxyalkanoates (PHA) by GC-MS?

Why methanol and sulphuric acid, used in the analysis of polyhydroxyalkanoates (PHA) methyl esters by GC-MS? Additionally, why do we typically use non-polar solvents in GC-MS?

22 July 2024 1,210 2 View

When making abraxane with Nab tech, why is 9:1 Chloroform&EtOH used as solvents?

Is it the best optimization ratio based on experiments?

22 July 2024 8,170 0 View

What is the solvent system required to run tlc for calixarenes?

If you don't understand my question let me know

21 July 2024 563 1 View

Convergence of absorbency values to determine the total phenolic content of several solvents?

I used several solvents and measured the absorbency and determined the total phenolic content, but the results were similar after dropping them on the titration curve; What is the reason, please help

17 July 2024 5,151 5 View

How Can I Resolve a Persistent Unwanted NMR Peak at 1.25 ppm?

Hello everyone, I am facing a consistent issue in my NMR spectra with an unwanted peak appearing at 1.25 ppm. This peak seems to vary with the amount of sample: it becomes more pronounced with...

15 July 2024 9,065 4 View

What is the suitable solvent of MIL-100 for chemotherapy?

I synthesised a nanocarrier by conjugation MOF (MIL-100) with folic acid for use in chemotherapy but the samples didn't dissolve completely in aqueous solution or DMSO. Instead, they only...

15 July 2024 2,414 1 View

Hey there, What is The best recommended solvent( safe for use) to dissolve or remove Z-90 Adhesive from ceramic surfaces ?

as of my knowledge z90 is acrylic based sealant adhesive.

09 July 2024 8,660 4 View