Atherosclerosis is a specific type of arteriosclerosis.
Atherosclerosis is the buildup of fats, cholesterol, and other substances in and on your artery walls. This buildup is called plaque. The plaque can cause your arteries to narrow, blocking blood flow. The plaque can also burst, leading to a blood clot.
Although atherosclerosis is often considered a heart problem, it can affect arteries anywhere in your body. Atherosclerosis can be treated. Healthy lifestyle habits can help prevent atherosclerosis.
As we know that Fat , cholesterol and other substances like Calcium , are the building block for the formation of plaque inside the lumen of coronary arteries , partially or totally block the blood flow to heart , leads to Ishaemia or infarction. There is no specific novel biomarkers to assess the progression of atherosclerosis. Besides the usual novel biomarkers like BNP , NT-Pro BNP , tropinin HDL-c , HDL function ,now researcher are eager to find out the novel biomarkers( produced by cardiac tissues) like miRNA , protein , fat by use of new technologies like Mass spectroscopy ,pcR bases array and MS based lipidomics
As atherosclerosis is the results of buildup of lipid s in the artery. I would say lipids profile including total cholesterol, triglycerides, low and high density lipoprotein are the main parameters. Also the oxidised LDL can also be used as a marker of atherosclerosis.
Besides the build-up of fats, cholesterol, and other related risk-related parameters, it is likewise essential to identify high-risk individuals by calculating the CAD risk score.
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