Are there any significant differences which can differentiate symptoms in Parkinson´s disease and symptoms in Parkinson´s dementia? Is there some significant deficit language, cognitive or executive functions?
Dear Sofia,
"The key brain changes linked to Parkinson's disease and Parkinson's disease dementia are abnormal microscopic deposits composed chiefly of alpha-synuclein, a protein that's found widely in the brain but whose normal function isn't yet known. The deposits are called "Lewy bodies".
Lewy bodies are also found in several other brain disorders, including dementia with Lewy bodies (DLB). Evidence suggests that dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementia may be linked to the same underlying abnormalities in brain processing of alpha-synuclein.
Another complicating factor is that many people with both dementia with Lewy bodies and Parkinson's disease dementia also haveplaques and tangles — hallmark brain changes linked to Alzheimer's disease.
Parkinson's disease is a fairly common neurological disorder in older adults, estimated to affect nearly 2 percent of those older than age 65. The National Parkinson Foundation estimates that 1 million Americans have Parkinson's disease. It is estimated that 50 to 80 percent of those with Parkinson's disease eventually experience Parkinson's disease dementia. "
http://www.alz.org/dementia/parkinsons-disease-symptoms.asp
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