Is it safe to be ingested? And how can I get rid of the stain? Is Lawsonia inermis toxic and should not be used in vivo? And can I separate the stain from the component that cause therapeutic effects?
Lawsonia inermis is used in vivo as dye or tattooing agent. though it is approved as hair dye by FDA, it's use as tattooing agent is contraindicated in america. yet, most of the countries in asia and africa use it for tattoing agent and consider it safer than artificial dyes. stain of Lawsonia inermis is because of Lawsone molecule which is released from leaves of Lawsonia inermis and is activated in acidic media hence lemon, tea leaves etc are used to increase it's efficacy. it's action is reduced in alkaline media hence any mild alkaline agent can be used to get rid of the stains. it is propagated to have many therapeutic action like anti-inflammatory, analgesic, and antipyretic effects and on application as hair dye, it is proposed to potentiate pentobarbitone-induced sleeping time. Lawsone can be extracted from Lawsonia inermis by liquid-liquid extraction procedure.
Thank you sir, i ve read a very old article belongs to 1960 , the author used the herb for the treatment of amoebiasis and diarrhea, the volunteers consumed the leaves water extract (intra oral) , my question is ... Is it safe to be ingested ? and if it is not at what dose it becomes toxic?