Thank you for your question, I can offfer partial answer.

Arrhythmias have genetic background and are the integral part of some inhered syndromes - see ECS guidelines for details - too many data to write them all. On clinical presentation the main influence is determinate by gene penetration in phenotype. This section would better explain expert in genetics. But once when guidelines criteria are fulfilled we are obligated to use proper therapy for primary or secondary prevention of death caused by arrhythmia and today we have means to do it. - medicaments or device therapy.