What are the epigenetic drivers behind the formation and progression of pediatric brain tumors?

More Tajinder Kumar Saini's questions See All

How to plot the significance level using line or dot pattern over a raster data plot in R usign base plot function?

After plotting the raster data using the plot() function in 'R'. How can we plot the other layer overlayed with dot/line pattern in place of color fill as shown in the picture...

06 January 2021 5,865 4 View

The ratio of hypocholesterolemic/hypercholesterolemic (h/H) fatty acids?

The following equation is generally used for the calculations of the ratio of hypocholesterolemic /hypercholesterolemic (h/H) fatty acids, or h/H fatty acids index (Santos-Silva et al. 2002;...

24 September 2020 9,939 5 View

What is the criteria used by IMD for delineation of Homogenous Monsoon Regions in India?

There are 6 Homogeneous Monsoon Regions. 1. What criteria has been used for determine their boundary? 2. Is there any officially published record mentioning the technicalities behind delineation?

31 August 2020 8,237 4 View

What is the best PCR strategy to genotype large deletions?

Hello, I currently setting up an experiment to study the role of a set of genes that span 150 Kilobases in my cell line. So I plan on generating a 150 KB deletion by nucleofecting Cas9 with 2...

03 June 2020 3,235 8 View

What are binary fingerprints in Padel?

On the official page of Padel, they say it calculates binary fingerprints along with others; I would like to know the names of all those binary fingerprints, which are calculated by the tool....

27 May 2020 9,350 6 View

What are the areas of human resource management where artificial intelligence is being used the most and in what way?

During the last some years, artificial intelligence (AI) is impacting most areas of management, including the different functions of the management of the human resource. Which aspects of HRM,...

24 May 2020 6,177 2 View

Transfection of large DNA plasmids into HEK293T?

Hi, I have been recently trying to transfect HEK293T with a large plasmid (http://www.addgene.org/53191/) which is around 15 Kb. I am using the PEI method to transfect this DNA. My protocol so...

14 February 2020 4,602 4 View

How we can increase carbon content in submerged arc welding process? Can we use CaCO3 and if yes then what is the chemical reaction?

In submerged arc welding, flux is used to adding alloy elements. Then what chemicals can we use for increasing carbon, manganese and silicon. And what are the reactions occur?

01 October 2019 4,766 1 View

How to implement 'Local CNN' as an Ensemble of Convolutional Neural Networks in MATLAB?

I am working on a project that involves implementation of an IEEE research paper given below. I am unable to construct the "Local CNN" described in the paper, which is an Ensemble of multiple...

01 July 2019 1,805 2 View

Can somebody indentify this organism?

Please see the uploaded photograph and a small video of an insect. Its body seems highly evolved to match with the vegetation to camouflage. Can somebody provide any infromation about this? Thanks

03 June 2019 4,336 13 View

Anyone plz suggest relevant topic for research in image processing+Deep learning.?

I have selected brain tumor images ...but now found that already lots of research done n this topic.

03 March 2021 5,774 3 View

What kind of food stuff increase the potentiality of human brain?

There are different kinds of food stuffs which we intake daily according to our requirements. Carbohydrate, protein, fat, mineral, vitamin, water are mainly working for the growth and development...

01 March 2021 831 2 View

Any specific pipeline or parameter to analyse total transcriptomics study of brain tissue samples?

I have two groups of brain samples, control and treated for example. It was total RNA nova seq sequencing. I tried all the available pipeline like: star+rsem+deseq2, Hista+stringtie+cuffdiff,...

27 February 2021 356 6 View

Can Ethovision store the generated data and video recordings directly to NAS system?

The size of data generated by Ethovision is huge. Having NAS system for data storage seems to be a good option, I am wondering whether Ethovision can directly store the data to the NAS system...

27 February 2021 6,350 2 View

Can MicroRNA cross the blood brain barrier?

In diseased conditions, many genes and gene products are visible in the bloodstream. So my question is whether we can find traces of microRNA which is involved in disease and disorder in blood serum?

24 February 2021 7,064 3 View

Are there any databases for gene co-expression or expression pattern clustering?

I am currently working on gene clustering based on co-expression pattern in mouse brain. The problem is I do not have some solid way to test my result. Are there any suggestions for databases...

22 February 2021 4,374 3 View

Can RNAscope be used to quantify the mRNA expression level of certain genes?

Hello, all, I want to explore the mRNA expression level of certain genes in the brain under physiological and pathological conditions. In previous studies, the researchers usually isolated the...

18 February 2021 1,518 1 View

How can I prevent bubbles from forming under a coverslip?

My colleague and I are having some trouble mounting 70 micrometer mouse brain slices. When we initially position the coverslip over the mounted slices, there are no bubbles but when we come back...

10 February 2021 3,580 1 View

Does anyone have a stack of images of action potentials or abnormal brain scans?

I need a stack of black and white .jpeg/.tiff/.jpg/.png images across time of either action potentials, neurons firing, or brain scans (comparing disease and normal brain, disease progression,...

09 February 2021 2,648 3 View

How do I fix tissue rolling while cutting frozen rat brain section with a cryostat?

I am cutting rat brain sections at 20um at -20C. The tissue is cutting nicely out of the O.C.T solution, but I can not get a decent section to adhere to the slide. I have included an image.

09 February 2021 1,345 5 View

Neha Kakran

This includes DNA methylation, histone modifications, chromatin remodeling, microRNAs, and long non-coding RNAs. Methylation of DNA, chromatin remodeling, and histone modifications regulate the chromatin and access of transcription factors to DNA and in turn gene transcription.

Mehrunnisa Qureshi

Mostly genetic in origion