Cholesterol is part of the plasma membranes of animal cells and serves in particular to regulate the fluidity of the membrane.
What are the consequences (pathologies, cell signaling ...), on an animal cell, if the synthesis of cholesterol is inhibited ?
Can you join me with articles and reviews about this ?
Thank you.
I'll send you a few references
https://www.ncbi.nlm.nih.gov/pubmed/9221828
http://europepmc.org/abstract/med/3612311
http://onlinelibrary.wiley.com/doi/10.1111/j.1432-1033.1977.tb11637.x/full
http://www.sciencedirect.com/science/article/pii/000527609090139O
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742364/
http://www.jbc.org/content/264/11/6230.full.pdf
They do not fully answer your question, but they will give you a general view about the effects of cholesterol synthesis inhibition. I recommend particularly the last article included.
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