Hi Qassim,

In terms of definitions and terminology, I assume you are referring to an old term (from the 1950s), "Childhood Aphasia" when you are speaking of "aphasia". The term "aphasia" is reserved for an acquired neurological impairment that impacts symbolic processing (including language) in those who have already acquired language proficiency but lose some aspects of it due to cerebrovascular accidents. The term "childhood aphasia" was adapted in the 1950s due to the superficial similarities between adult "aphasia" and severe child language impairments. the term, however, is not typically used anymore -- at least in the United States. To respond to your specific question about severe childhood language impairment and (perhaps) mutism, there have been two genes that have been implicated in severe language difficulties (as well and other learning disabilities). first (and most likely) is the KIAAO319 gene....also found in specific language impairments and tyhe LITRK6 gene that may result in hearing and (consequently some aspects of mutism). Neither gene is implicated 100% or even completely..and the mechanisms are still not determined...but those are the two genes that I am aware of. Look at the work of Mabel Rice and colleagues. Hope this helps

jack

فقدان القدرة على الكلام هو مصطلح يطلق على مجموعة من الاضطرابات اللغوية الناتجة عن تلف في الدماغ، ولتشخيص المرض يلاحظ الفرق في سلامة النطق لدى المريض من قبل الحادثة أو المرض ومن بعدها.

Dear,Dr.Salah

I thanked you very much

Regarding

Dear, Dr.Damico

Thanks a lot for your scientific and simply answer.

Greeting

Thanks