What are the conditions to do the reaction of carboxymethylation of aromatic amine?

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Jürgen Wintner

You can conduct the carboxymethylation with chloroacetic acid or sodium chloroacetate with sodiumhydroxide. See attachment. Don't use formaldehyde (mentioned on the procedure), because this is for crosslinking and forming of resin!

T. H. Al-Noor

https://pdfs.semanticscholar.org/38e4/cc4387e3ec3b9c05515abe1025f361a15ff9.pd

Rasim Farraj Muslim

Dear Harrache Rabiaa

My answer is in the attached picture

Regards

Sikandar Khan

Please have a look at these useful links.

https://iris.unive.it/retrieve/handle/10278/24140/22940/13.%20Springer%20final%202008.pdf

Sandeep Chandrashekharappa

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DOI:10.1016/j.tetlet.2018.08.049