Dear Vinesh

there are several techniques used for the study of particulate matter, the question now arises, what kind of study do you plan to do, what are the objectives of your study.as you have mentioned cardiovascular diseases in your question. As it has been proved by ample number of studies the primary cause of the cardiovascular disease could be the PM 2.5. (several other factors and pollutants could also be the reason). Hence forth the monitoring of the PM 2.5 can be better done with several instruments. few of them could be RDS, GRIMM spectrometer, OPS, SMPS, Dusttrack(TSI made) etc.

By mention of cardiovascular diseases I suspect you mean PM10 and PM2.5. You may find an impact on cardiovascular systems from other particle sizes but that may be down to particle composition (i.e. does it contain heavy metals, VOCs, PAHs etc) as opposed to size.

As Satoshi points out, it would be good to know whether you need to just identify particle size or if you need to collect samples, because collection methods vary significantly depending on which one is most suitable.

If you're looking for pollutants contributing to cardiovascular disease don't forget to look at the gaseous pollutants (e.g. NO2, Ozone etc.) too. They're very important.

Thanks Ben,  Rohit and Satosi,

I want to do study on chemical composition and  structural variation of both PM10 and PM2.5

For that you need to collect samples, gravimetrically (collect samples through filter paper) the instrument which I mentioned would do the need full.

The best approach could be, at the beginning, a characterisation of PM in terms of chemical composition. I would suggest the evaluation of soluble ions (SO4, NO3, Cl, etc, NH4, Na, K, etc) by using the denuder techniques and the evaluation of EC/OC. If analytical resources are available, XRF could provide information about soil dust (Si, Fe, Al, etc.). In this way you may have  an idea about the contribution of soil dust, primary sources and secondary aerosols. After that, you may refine the investigation with additional parameters fitting your specific scientific targets.

In the EU 24-hour PM10 limit value of 50 μg/m³ with a maximum of 35 exceedances (equivalent to an annual mean of 30 μg/m³) was linked with an annual mean of 40 μg/m³. The noncompliance with the 24-hour limit value give the misleading message, that health problems are mainly due to short-term changes in air pollution. You should rather look for long-term and latent effects in cohort studies, if possible related to PM2.5.

The fast technique to establish the diagnostic ratio, source apportionment is to combine many techniques such as EC/OC, DOC and ionic chromatography

High volume air sampler with other common analytical techniques which depends on the interest of your pollutants is needed.

In my opinion, apart from gravimetric analysis, characterization should include metal analysis, soluble ion analysis and EC/OC analysis. Further one can collect data related to cardio vascular diseases from the hospital in study area and correlate it with the analysis of PM.

Check EPA.COM