People with physical disabilities especially the acquired disabilities are at a higher risk of facing mental disorders such as depression and anxiety. This may be due to isolation and discrimination especially from the family members and close relatives and friends.

Disabilities especially chronic ones may also affect sexual urge, performance and relationships leading to low arousals. According to research in the journal Sexual Medicine Reviews, almost 60% of individuals with a disability report a decline in their sexual activity and satisfaction post-injury or illness, with partnered individuals often facing similar challenges.

Sexless marriages are also associated with acquired disabilities. sexless marriage is a situation whereby couples can have fewer than 10 times per year resulting to serious psychological problems. A 2014 study published in JAMA Internal Medicine found that 16% of married couples report having sex less than 10 times a year, and those in sexless marriages often have lower relationship satisfaction and increased symptoms of depression.