The specificity of this question is mainly focused towards medicine, pharmacy, biology, Nursing and other allied health sciences.
Meyer and Land described threshold concepts as ‘portals’ that open up ‘new and previously inaccessible’ ways of thinking about something and ‘a transformed way of understanding or interpreting or viewing something without which the learner cannot progress’ (Meyer & Land, 2003).
A threshold concept is thus seen as something distinct within what university teachers would typically describe as ‘core concepts’. A core concept is a conceptual ‘building block’ that progresses understanding of the subject; it has to be understood but it does not necessarily lead to a qualitatively different view of subject matter.
So, for example, the concept of gravity — the idea that any two bodies attract one another with a force that is proportional to the product of their masses and inversely proportional to the distance between them — represents a threshold concept, whereas the concept of a centre of gravity does not, although the latter is a core concept in many of the applied sciences (Meyer & Land, 2003).
References:
Meyer, J., & Land, R. (2003). Threshold concepts and troublesome knowledge. Edinburgh: University of Edinburgh.