Not only in Nigeria, poor, hard working people of the globe who face infections of different types everyday and achieved a very good resistance power against many microorganismas as well as take succulent natural plant parts as spices or as part of daily food, are far more resistant to COVID 19 than the people having no such status.

It is my idea on the topic.

Thanks.

I suspect that the use of chloroquine, an anti-malarial drug, by Africans plays a large role in the low incidence of Covid-19.

We note that people with low incomes and poor environments are more likely to fight coronavirus than others. Note that poor people have less health insurance and are more resistant to disease than people with premium health insurance. Genetics has an effect. Geographical regions have an effect. Vegetarian food and low-animal foods, or eat more variety of vegetables and fruits at the expense of animal food, help build natural resistance.

https://www.ng.undp.org/content/nigeria/en/home/covid-19-pandemic-response.html?cq_ck=1587691488777

Natural adaptation, because they are threatened by many pathogens, because of their poor living conditions, and the use of antimalarial products, such as chloroquine

Nothing clear yet

Testing every citizens for covid 19, and giving every tested a personal identification number ( pin). Quarantine every covid19 patient and we carried on with our daily activities with our migrations monitor and equipped with testing personnel and equipments.

You are making an enormous mess. SARS-CoV-2 is a virus, not a bacterium or a fungus. There is no immunity or natural resistance due to the lifestyle of poor people. This may apply to bacteria. To have virus immunity, one must have been infected with the virus and survived. Across the world, the poorest populations are succumbing to thousands of deaths. They are the ones that pay the biggest price.

Certainly the high ambient temperature, a low relative humidity and a strong ultraviolet irradiation of the sun, decrease the environmental viral load and this decreases the total number of infected. The virus has some proteins (Orf3a and Orf7a) that specifically block the host's immune defenses. The greater the number of viral copies that infect a person, the deeper they enter the respiratory system, through the aerosols, the more serious the infection. Aerosols are much smaller particles than the famous droplets and are emitted by speaking, and therefore they are much more dangerous and remain to float indoors for about 12 hours, concentrating more and more). They cover far greater distances than droplets, even hundreds of meters outdoors. The viral particle threshold for getting infected is around 5000 - 10,000 viral copies. With fewer copies, the body defends itself well. A serious infected produces 100,000 viral copies as af the virus. The rest, if we eat vegetables or fruit, or if we drink hot or cold tea, or if we eat anything else, only affects the epigenetics of the individual making it a specific human phenotype with probability of infection similar to many others.

If this guy speaks for a few minutes, without a mask, with an infected, sick or asymptomatic, and loads his lungs with over 10,000 viral copies, he has a very high probability of becoming infected and having a serious form of covid19.

https://www.who.int/docs/default-source/coronaviruse/covid-strategy-update-14april2020.pdf?sfvrsn=29da3ba0_19

Dear Dr. Giovanni Colonna ,

I do not agree with you.

From my small experience, I can say that addition of Mycobacterum bovis BCG killed cells with some vaccines increase their potentiality to a few folds!

So, there are many effects of resistance against one organism with resistance against another.

Activation of macrophase is one point, but their may be many others!

Thanks.

I am not interested in epidemiology, pandemics, or in the spreading ability of the virus. This should interest those who govern a people to reduce damage to the population. Nor am I interested in knowing how to buffer the numerous symptoms that the disease manifests. This affects doctors to reduce victims. Remembering that all this does not lead to cure the disease, only to contain the losses. The climate interferes with the viral load; the facts say. This also reduces losses. I have little faith in a vaccine that is efficient and fast, without side effects, simply because to date the facts say that in the past twenty years no one, after various pandemics, has made a vaccine against corona-viruses, and today's virus it is very similar to yesterday's. The facts also say that many healed people reinfected after a few months. The levels of anti viral immunoglobulins last very little, after all, it also happens for many other viruses. The big pharmaceutical companies are leading the research, pushing towards the hope of the vaccine or the reuse of existing drugs, but only for reasons of big profits. A serious way to deal with the problem is to discover the molecular mechanisms that the virus uses to block the host's defenses and manage its metabolic response. This is the most correct way to solve the problem because it is the only one that allows you to design a drug capable of curing, but it is the longest approach and takes a lot, but a long time, requires large investments and is outside the logic of the great pharmaceutical industry. In science, a single scientific work, even an important one, is never true knowledge, it is only until it is confirmed by many other laboratories around the world. In this era, the results of a single paper are considered as the confirmation results of ten laboratories.it is only a hypothesis. While to day, it is a TV show. This blurs the minds, creates chaos, and pushes on wrong paths. Everyone should do his job for which he has prepared himself with years and years of hard and serious activity.

Greetings

Thank you all for your comments and recommendations.