At puberty age and due to fatty derm and epiderm,sebaceous glands could be blocked and hence Probionobacterium acnes mainly make local skin scars or the what is so called ACNE. In such skin scars infections can develop and secondary organisms such as Staph aureus can cause more infections.
Propionibacterium acnes has been recently reclassified as Cutibacterium acnes.
Article The natural history of cutaneous propionibacteria and reclas...
An important factor influencing the formation of acne is the metabolism and genetic profile of the skin microorganisms. The numbers of Propionibacterium acnes (Cutibacterium acnes) in acne patients and healthy people were at a similar level; however, changes in the virulence/ metabolic profile of these bacteria have been noticed. Strains isolated from acne patients had a higher level of operational gene units (OGUs) associated with the production of bacteriocins, toxins and factors linked with bacterial genetic modifications. Strains isolated from healthy people possessed many OGUs involved in microbial metabolism and nutrient biosynthesis, including production of short chain fatty acids (SCFA). What's more, there was also an increase in the number of P. acnes (C. acnes) phages in healthy people and the elderly (who rarely suffer from this disease), suggesting that phages are an important element shaping the functioning of skin microbiota.
Article The balance of metagenomic elements shapes the skin microbio...
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