Dear Jan Verner

maybe it's worth to test the DX5 clone directed against the CD49b antigen.

Please check the following example.

https://www.biolegend.com/en-us/products/pe-anti-mouse-cd49b-pan-nk-cells-antibody-234

In addition, Petter Höglund's group used anti-NK1.1 (PK136) mediated NK cell depletion in NOD mice and subsequently stained with the aforementioned clone, which is a good indicator that this should work.

Article Broadly impaired NK cell function in non-obese diabetic mice...

Biolegend also suggests this antibody for NK cell monitoring in mouse strains that do not express NK1.1, like BALB/c/J, SJL/J, AKR/J, CBA/J, C3H/J. For more details check on the strain dependent alloreactivity of anti-NK1.1 clone PK136 check

https://www.jimmunol.org/content/jimmunol/176/12/7511.full.pdf

Best,

Michael

Thanks for your proposal, Michael.

Best

Jan

I agree.