mRNA vaccines against Covid-19 may worsen cronic autoimmune disease?

Example: if a patient suffers of a 15 years psoriatic arthritis and gets Leflunomide (20 mg/ or 40 mg per day) and methilpredisolone (4mg per day). Then, his turn arrives to be vaccinated against...

11 January 2021 7,788 11 View

What about new vaccines for Covid-19 and autoimmune diseases ?

Many people, who are going to be vaccinated soon, suffer a variety of autoimmune diseases (i.e. reumatoid arthritis or psoriatic arthritis and many others). In particular, some of them are...

05 January 2021 6,069 3 View

Are there any biomarker to find the proper treatment for patients affected by psoriatic arthritis?

Cancer research has developed precise biomarkers to use a proper cure for different kind of cancers. Why there is no proper biomarker to find the precise treatment in autoimmune desease, such as...

25 July 2019 9,710 4 View

What is the significance of (isolated) high titers of IgG anti GD1a antibodies in an older patient with polyneuropathy?

Remote history of Campylobacter infection with reactive arthritis, and Spitz nevus (UMP). Arthropod exposure in Zika/ChikV endemic area prior to emergence of length dependent, sensory PN with...

18 February 2021 8,719 1 View

How to perform EEG classification of Alzheimer and control groups?

I am doing a project on classification of EEG signals of Alzheimer's disease and control groups. Previously, I extracted the alpha power of the EEG signals and found out the strengths. I want a...

18 February 2021 8,502 2 View

Does anyone have a stack of images of action potentials or abnormal brain scans?

I need a stack of black and white .jpeg/.tiff/.jpg/.png images across time of either action potentials, neurons firing, or brain scans (comparing disease and normal brain, disease progression,...

09 February 2021 2,648 3 View

Patients with chronic kidney disease could get COVID-19 vaccine?

04 February 2021 278 4 View

How can you accurately induce calcium overload and measure membrane potential in cultured Tg2576 neuronal cells using whole cell patch clamp method?

Hi there, I'm currently working on a project where i need to design an experiment but as i have little to no experience with this level of experimental design and no face to face help i am really...

22 January 2021 6,728 3 View

Where can I get a Music therapy database for Alzheimer's Disease?

I am working on the effect of music therapy on persons with Alzheimer's Disease. I require EEG signals of healthy individuals and people with Alzheimer's Disease/Dementia that have undergone music...

22 January 2021 8,613 5 View

What is the best nanoparticles that can be easily prepared & can be used in silencing the BACE1 gene for prevention of Alzheimer disease?

I want to do a research about the nanotechnology and management of Alzheimer. I found a lot of ideas about nanoparticles that already studied in that field but I do not know which of them is the...

20 January 2021 1,052 3 View

What is role of chronopharmacology or circadian rhythms in metabolic diseases including obesity, diabetes and cardiovascular diseases?

Chronopharmacology is branch of biological science which deals with daily life, sleep and wake, day and night, feeding and fasting and other effects. we can manage many diseases including...

18 January 2021 9,045 3 View

Is there no general protocol for vaccination study?

Hi, I searched vaccination study to know which MLD50 is suitable for influenza virus study in pubmed. But why every vaccination and challenge conditions are different? Is there no guideline or...

16 January 2021 7,984 3 View

Does use of hand sanitizer negatively impact the skin microbiome?

Hello, Most hand sanitizers contain 60-80% alcohol. Alcohol destroys organisms including bacteria, fungi, protists, and enveloped viruses by breaking down the plasma membrane. In recent...

16 January 2021 6,923 11 View