Weird TEM pictures, does anyone know what this is?

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Krishna Bharat Lankamsetty

you have not mentioned the material name. anyhow if a material has organic moiety, during TEM analysis you can see them to melt or deform and appear on the particles... this may be one reason but not sure what the image is.

Michał Kulus

Any chance that you could isolate the viruses along with the EVs? Please compare with Figure 2 in article below:Article Distinct Morphology of Human T-Cell Leukemia Virus Type 1-Li...

I am not sure, however; higher magnification would tell us more. Now I cannot exclude that it's just a damaged Formvar.

Na Na

Michał Kulus Hi Thanks for your reply. My particles are about 1uM large, I would think it's too big for viruses but I'm not sure.