Water act as solvent system in organic reactions but in chromatography (HPLC and GC) why we do not use generally water as solvent system?

09 September 2017 1 1K Report

water as solvent in organic reaction and chromatography?

In GC we use volatile solvents or easily volatilized solvents. Additionally, water needs 100°C for boiling, hope your components not degradate before reaching 100°C.

In HPLC, it depend to the polarity and affinity

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