Bernhard Müller

Dear Bernhard,

the effects of vitamin d on different inflammatory conditions are not well established (inconclusive), but your theory might be accepted from molecular and immunological aspects. [https://pubmed.ncbi.nlm.nih.gov/21067953/]

in the case of nutrient deficiencies and their interaction with vitamin d activation/ bioavailability, there is evidence parallel with this.

in addition to these items (K, Mg), I think you need to also focus on "selenium" because there is evidence that is directly/ indirectly support the interaction [see "Interaction of selenium and vitamin D and its relevance to atherosclerosis" by matthew et al.]

There is evidence that the quality of vitamin D supplements can impact their bioavailability and effectiveness in the body. Vegan production, duration of storage, and other factors can affect the quality of vitamin D supplements.

For example, vitamin D3 supplements derived from lanolin (a wax-like substance found in sheep's wool) are the most common type of vitamin D supplement. However, some people prefer to use vegan vitamin D3 supplements derived from lichen. While both forms of vitamin D3 are effective, the bioavailability of vegan vitamin D3 supplements may be lower than that of lanolin-derived supplements.

Additionally, the quality of vitamin D supplements can be affected by the duration of storage. Vitamin D3 is sensitive to light and heat, and prolonged exposure to either can degrade the quality of the supplement. Therefore, it is important to store vitamin D supplements in a cool, dark place and to use them before their expiration date.

Other factors that can impact the quality of vitamin D supplements include the presence of contaminants, the form of the supplement (e.g., liquid, capsule, tablet), and the presence of complementary micronutrients like magnesium and vitamin K2.

Overall, it is important to choose high-quality vitamin D supplements and to consider factors like production methods, storage conditions, and complementary micronutrients when using vitamin D to support immune function and overall health.

Yes, vegan production, duration of storage, and other parameters of quality can impact the bioavailability of vitamin D supplements.

For example, vegan vitamin D3 supplements derived from lichen may have lower bioavailability compared to animal-derived vitamin D3 supplements, such as those derived from lanolin. This is because the vitamin D3 in lichen is in the form of D3 precursors that need to be converted by the body into active vitamin D3. This conversion process can be less efficient than the conversion of animal-derived vitamin D3 into its active form.

Furthermore, the duration of storage can affect the bioavailability of vitamin D supplements. Vitamin D3 is sensitive to light and heat, and prolonged exposure to either can degrade the quality of the supplement. Therefore, it is important to store vitamin D supplements in a cool, dark place and to use them before their expiration date.

referrence :

Article Vitamin D: sources, physiological role, biokinetics, deficie...

Article Serum 25-hydroxyvitamin D status of vegetarians, partial veg...