If I am using a standard drug which is not in a salt form and the formulation is in salt form(sodium, palmitate etc.) then I have to use the correction factor for the calculation. But if both the standard drug and the formulation are in the same salt form(ex. dicloxacillin sodium) then also I have to use the correction factor or I can calculate directly without using correction factor as both are in the same salt form? Kindly suggest me on this
As both the formulation and standard drug are in same salt form.The correction factor will be 1 so i think correction factor is not required in this case.
thnx..are you sure? As I am also thinking on the same line but not certian about it.
Hi Bhupendra,
i am herein attaching link of one research article.go through the page no.920. this may help u and act as supporting evedience.
http://rasayanjournal.com/View-document/592-THE-ROLE-OF-RELATIVE-RESPONSE-FACTOR-IN-RELATED-SUBSTANCES-METHOD-DEVELOPMENT-BY-HIGH-PERFORMANCE-LIQUID-CHROMATOGRAPHY-HPLC.html
All the best
Hi, if your analyte is in the same form as your reference (standard) there is no need for using a correction factor, but if you want to express your analyte (drug) as a different specie you'll have to correct by a factor.
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