One would judge the quality of a (pharmaceutical) paper by assessing its publishability, and asking the question: Does this paper add to our knowledge of formulation XXX?
But what you will say about ISI (Thomson Reuters) and other impact factors. Does this tool exactly indicate the worth of research paper? Does papers other than those which have impact factor are not worthy?
IFs do not indicate quality but how many times has a paper been cietd. that means a quality paper that is not visible will have low IF, while not so good papers which are too visible wi be well cietd, hence high IF. another aspects that affects IF is who cites who? a paper with more citing will attract author to be associated with it. etc
The Thomson Reuters impact factor will measure how many (positive AND negative!) citations there are to your paper from subsequent papers within the Thomson Reuters fold only. Citations from other sources and from books do not count. Patents, pill profits and PhDs arising from your paper also do not count.
My advice to you is to direct your paper to the most fitting journal.
Yes in the field of research there is a race to publish research article in isi (thomson reuters) based impact factor journal. It is suggested that after publication in these journals the research paper will be worthy and of highest impact.