Can the role of lectins in cellulart pathways be somehow generalized, esp. in the context of their binding to sialic glycan receptors on the endothelial cells surface?
These two paper links provide valuvable information two you:-
1-An alternative pathway of T-cell activation: a functional role for the 50 kd T11 sheep erythrocyte receptor protein.
SC Meuer, RE Hussey, M Fabbi, D Fox, O Acuto… - Cell, 1984 - Elsevier
2-Evolution of the lectin–complement pathway and its role in innate immunity
T Fujita - Nature Reviews Immunology, 2002 - nature.com
These two paper links provide valuvable information two you:- 1-An alternative pathway of T-cell activation: a functional role for the 50 kd T11 sheep erythrocyte receptor protein. SC Meuer, RE Hussey, M Fabbi, D Fox, O Acuto… - Cell, 1984 - Elsevier 2-Evolution of the lectin–complement pathway and its role in innate immunity T Fujita - Nature Reviews Immunology, 2002 - nature.com
There seems to be some glitch in the RG's software - the questions stays marked as "new" and with no answers at all. However, just by a bit of serendipity I've found a moment ago that there in fact was an answer, although it stayed invisible all the time since posted - so I'm copying it again just in case it might be lost (hopefully not, and if it will by doubly visible - my apologies):
"Tarkeshwar Singh · 4.88 · Indian Institute of Science Education and Research Kolkata
These two paper links provide valuvable information two you:- 1-An alternative pathway of T-cell activation: a functional role for the 50 kd T11 sheep erythrocyte receptor protein. SC Meuer, RE Hussey, M Fabbi, D Fox, O Acuto… - Cell, 1984 - Elsevier 2-Evolution of the lectin–complement pathway and its role in innate immunity T Fujita - Nature Reviews Immunology, 2002 - nature.com"
@Tarkeshwar, thank you - it was perhaps sitting here for almost two weeks invisible - I'll read these two works and possibly will be back with more questions :)
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