That is more alarming and also may lead to cytokine storm leading to self destruction of body cells... And ultimately death of the person

Cytokine storm was also a big problem in Spanish flu dear Ruqia Quansar

Ironically, in most cases, it is the strength of their immune response that can put a healthy person at risk for complications associated with the flu. While most of the time a strong immune system is key to keeping an infection in check, sometimes the body’s reaction to being infected with the flu presents the greatest danger to an otherwise healthy person. 

“A cytokine storm is generally what leads to otherwise healthy young people dying of the flu,” says David Martin, Senior Medical Director at Pfizer. “We saw that in the flu pandemic that happened at the end of World War I and we’re still seeing it today.”

https://www.breakthroughs.com/foundations-science/inside-cytokine-storm-when-your-immune-system-too-strong

The Spanish flu killed quickly, and it killed in huge numbers. Other flu pandemics in modern times have been far less deadly. Why?

Besides replicating very quickly, the 1918 strain seems to trigger a particularly intense response from the immune system, including a ‘cytokine storm’ – the rapid release of immune cells and inflammatory molecules. Although a robust immune response should help us fight infection, an over-reaction of this kind can overload the body, leading to severe inflammation and a build-up of fluid in the lungs that could increase the chance of secondary infections. The cytokine storm might help to explain why young, healthy adults – who normally find it easier to shake off flu – were the worst affected, since in this case their stronger immune systems created an even more severe cytokine storm.

BBC

https://www.bbc.com/future/article/20181029-why-the-flu-of-1918-was-so-deadly

Hi ;

One of the particularities of the new coronavirus is its ability to generate a phenomenon called "cytokine storm", i.e. the massive release of molecules involved in the control of immunity. This form of hyper-inflammation is thus pointed out as a factor that may explain not only the severity but also the mortality associated with the new coronavirus. This runaway mechanism, known for many years, is not, however, unique to Covid-19. "Cytokine storms are associated with a wide variety of infectious and non-infectious diseases, such as influenza-related bacterial superinfections, graft-versus-host disease, multiple sclerosis and pancreatitis.

With my best regards

Yes, we know the effects of cytokine storm during Spanish flu dear Doufnoune RACHIDA Rachida and thanks for sharing.

Day in day out we get alarming report on Covid-19 pandemic related matters. The only question that runs through my mind is "when will this whole menace end"?

As a researcher we have to be more rational than emotional, dear Stephen Taiwo Onifade . It's no way to think for ending soon. We can try for control only. After that we can go for elimination and eradication. Unluckily, it's beyond control now.

Dear Muhammed;

Cytokines (whose family includes interferons and interleukins, among others) are used to inhibit viral replication in infected cells, to ensure the exchange of information between white blood cells, or to stimulate the production of cells in the blood system. While cytokines, and the inflammatory response they produce, are essential to the immune system's response to a pathogen, the problem arises when cytokines are secreted in excessive amounts, preventing any neutralizing mechanism. This immune system runaway can then lead to a cascade of deleterious effects, such as a sudden drop in blood pressure, pulmonary oedema, acute respiratory distress or a decrease in the contractile force of the heart muscle. All these effects on the organism can lead, in the most dramatic cases, to the death of the patient.

With my best regards

Yes, we know about the effects of cytokine storm among young and adults during Spanish flu and the term is more familiar since then, dear Doufnoune RACHIDA Rachida