Are there any published articles of how a clinical setting can influence results of a study compared to the results when consumers purchase the 'therapeutic product' from a source without influence of a health professional or clinical setting?
Thank you very much, will be very useful!
I need to add what I am specifically looking for, is an article that will also address the difference between a weight-loss study done in a clinic/medical setting, versus a patient/consumer purchasing the same product via the internet or a retail store - i.e., the latter excludes the influences of the clinic setting, the perception of health professionals in attendance, etc.
These links may help you:
http://bmjopen.bmj.com/content/5/11/e009676.full
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938946/
http://annonc.oxfordjournals.org/content/22/Suppl_7/vii10.long
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-32252014000200109
Thank you, all useful!
Also found this most relevant one:
Factors That Can Affect the External Validity of Randomised Controlled Trials
Rothwell PM (2006) Factors that can affect the external validity of randomised controlled trials. PLoS Clin Trials 1(1): e9. DOI: 10.1371/journal.pctr. 0010009
http://journals.plos.org/plosclinicaltrials/article?id=10.1371/journal.pctr.0010009
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