There was a comment today on twitter highlighting that statistical significance and clinical significance are two different things, clearly. However, It is not uncommon for authors of reviews to extrapolate a minimal positive or negative statistical effect from a research piece and use it to support whatever point that they are trying to endorse. Researchers may tell us that a treatment is or is not statistically valid, but how will this translate into the clinical environment?

This makes it difficult for the clinicians who want to try to be lead by research in their practice, but are perhaps less adept or experienced in sifting through research and determine quality, and thus end up accepting or misreading low statistical effect for benefit it the clinical setting. How can we ensure that dissemination of information is correctly interpreted for better or for worse in relation to patient care, and that clinical significance is differentiated correctly from statistical significance?

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