Dear All,

The technical challenges associated with magntic fluid hyperthermia is to correctly assess  tempreature elevation, Fluid distribution  and Heat deposition. Does anyone know any rebust strategies proposed for the afermentiond limitations?

In the description of clinically approved NPs for MFH, ( NanoTherm®therapy ) commmercilized by MagForce Nanotechnology company it has been mentioned that :

The fluid has a visible contrast in therapeutic concentrations on a CT scanner and can be detected down to 0.01 g/l Fe in the MRI.

Howerv in some publications the fluid distribution detection has been proposed as a technical problems of this current system which is not geing to be a concern because of high detection coefficency (0.01 g/l Fe in the MRI).

Any comments are highly appreciated.

cheers,