Simulation of RNAs containing modified residues or tautomeric Gauanine

29 May 2017 1 4K Report

I would like to get he recent amber force field (topolgy-parameter) for performing MD simulations of RNAs containing modified residues. More importantly how to simulate system containing Guanine in Tautomeric form (force field)?

Semen O. Yesylevskyy

You need to modify topology of your guanine residue to simulate tautomeric form. Exact procedure depends strongly on md software which you use.

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