do you use a Waters LC/MS or only LC-system? For LC/MS-systems (MS= ZQ or SQD) you have the opportunity to connect an analog detector signal with the analog input of the ZQ or SQD. The analog signals are then recorded as additional detector signals during the run. It is not possible to control the analog detectors via MassLynx or Empower. You have to do this manually via the detector display.