Article Sex Differences in Autism Spectrum Disorder: a Review
Up to my understand and research work, I believe that estrogen might be protective against glutamate excitotoxicity. So please I need your opinion in this regard
Autism as a Neurodevelopmental disorder is known to greatly affect males than females. It is very interesting to understand different mechanisms that might be related to male susceptibility or female protection such as sex hormones. Understanding the differences in vulnerability of both sexes’ to develop impaired gut microbiota, oxidative stress, glutamate excitotoxicity, and neuro inflammation as etiological mechanisms of autism.