Dear colleages,
I am interested in solvent mixtures information about handling and security considerations. These solvents mixtures are common in liquid chromatography, i. e.
Thank you,
Best regards.
Dear Sir. Concerning your issue about the security sheet about solvent mixtures. Panama Canal Authority (ACP) Safety and Occupational Health Manual, Section 14.5, issued and revised by the Safety Division (ESS) in January of 2000, on the handling and storage of liquids, flammables and solvents. This standard updates the existing information and includes combustible products. Many chemical substances that are used to dissolve or dilute other substances and materials are called ‘solvents’. Industrial solvents are often mixtures of several individual substances. They can be found under a variety of trade names. I think the following below links may help you in your issue:
https://www.pancanal.com/eng/legal/reglamentos/security/safety/128en.pdf
http://www.hse.gov.uk/pubns/indg273.pdf
http://www.utdallas.edu/ehs/download/Chemical_and_Hazardous_Materials_Safety.pdf
https://www.shell.com/content/dam/shell/static/chemicals/downloads/products-services/solvents-flammabilityguide.pdf
https://www.unodc.org/documents/scientific/Disp.Manual_English.pdf
Thanks
Dear Mr. Hussein.
Thank you very much for your valuable answer.
Not "Security", but SAFETY.
The same companies that sell the HPLC grade solvents also have manuals which contain the MSDS documents with the warnings and hazards too (you can obtain for free or purchase them). This should be part of the required chemical training for anyone working in that area.
Dear Mr. Letter.
Probably I did not explained with sufficiency my question. It is not about solvent as such, but with respect to solvent mixtures, We do not buy mixtures, it is prepared in house.
Safety information about an individual chemical sustances is available from provider. My concern is about mixtures.
Thank you very much.
Regards,
Gustavo.
Thank you for the clarification. Your question is very broad in scope. Since there is an unlimited number of possible solvent mixture combinations possible, I would strongly suggest that you consult with a local chemist at your school for help in addressing your concerns. Perhaps give them some examples of proposed mixtures to evaluate?
For most NP/RP chromatography applications, we do not "mix" mobile phase solutions together which are more hazardous as a mixture then they are alone. Strong acids and bases always present a concern which should be addressed with standard safety precautions. Some solutions will show a mild exothermic or endothermic reaction when first mixed, but it often will quickly dissipate (e.g. MeOH/Water). Some solvents in neat form can form peroxides or other unstable forms over time (i.e. THF), but these can be purchased with stabilizers added to reduce any threat. Once you identify which materials you wish to combine, some basic chemistry knowledge and review of the MSDS may reveal any potential concerns.
Dear Mr. Letter
Thank you very much for your orientation.
Have a nice day, Kind regards.
Dear Gustavo, I suggest you that search the guidelines of the OMS related with Management of Chemical Wastes or Management of Chemical Substance. Search wich is the guideline that Colombia select to follow and search this in it. Maybe you can find a light in the document of a norm called RESPEL (Residuos Peligrosos) on the CVC page.
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