I got a small respond from Autism Spectrum Disorder (ASD) Parent (56), I have been waited for 2 months and I tried to reach them in many ways and different time. Can I stop and analyze the data and compare the two groups Children with ASD (n=56) and without ASD (n=234)?
Thank you in advance,
Laila
Dear Laila, as Joanne rightly said, you can compare two groups of different sizes but the statistical significance of the result will decrease (You can do this for preliminary studies). Indeed, it is preferable that the size of the two groups is similar and that the two groups have similar characteristics for sex and age. If the two groups have the same characteristics, the statistical power of the results will increase. Furthermore, in the event that the disease develops in a given population of a circumscribed geographical area, the best control group are healthy subjects of the same population.
Alessandro
Thank you Joanne andAlessandro for your answers! I know that they should not be the same sample size... the problem that I don’t know the number of Autism children in my country ( the government does not have this data). Thus, I’m confused! I know that the autism group in real life are less than the typically developmental children. I want to puplish the study, so do you recommend to do a mixed study to bring more depth information from the autisim parent group?
To make the puplish chance increased and not rejected from the publisher review ?!
Before we say Yes or No , How is it that they are different in psychological traits, characteristics, and behavioral response rates
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