Dear Tarik,

The physical modification is the preferred way to obtain PVA derivatives intended for pharmaceutical or biomedical applications since the chance to find toxic residual crosslinking agents is avoided. This is in contrast to the chemical modification method in which toxic residual could be present in the final product.

For more on PVA and reticulation of PVA, please see the following links which contains a recent review on this topic:

http://www.academicjournals.org/article/article1404813310_Marin%20et%20al.pdf

Hoping this will be helpful,

Rafik

Dear Tarik,

The physical modification is the preferred way to obtain PVA derivatives intended for pharmaceutical or biomedical applications since the chance to find toxic residual crosslinking agents is avoided. This is in contrast to the chemical modification method in which toxic residual could be present in the final product.

For more on PVA and reticulation of PVA, please see the following links which contains a recent review on this topic:

http://www.academicjournals.org/article/article1404813310_Marin%20et%20al.pdf

Hoping this will be helpful,

Rafik

This technique depends on the used crosslinker. But from our laboratory experiments the thermal crosslinking is better and provides more details.

Dear all

Thank you very much for your answers.

Best wishes