Beside acute gout arthritis, hyperuricemia can cause destruction of the affected joint by chronic deposition of uric acid crystals and nephrolithiasis by uric acid stones; and kidney disease.

Hi Divya Ganesan

* Exposure doses completely vary depending on the region from where the PM 2.5 particles are collected (Low, moderate and highly polluted regions) or based on its compositional analysis.

* Similarly, are you looking for human exposure or mice? If mice then deposition would depend on the route of exposure (Intranasal, Inhalational, Instillation).

Thanks,

Thank you so much for your valuable answer... i am looking for human exposure.