Does "tissue remodeling" in humans involve "new tissues" or only "old tissues"?
Dennis
Dennis Mazur
Hello,
in my field of osteology and bone histology, the concept of remodeling plays an important role. Old bone tissue is removed by resorption and then replaced with newly synthesized lamellar bone. I don't know if this will help you, since you seem mostly concerned with the discipline of cardiology.
But while most remodeling in skeletal tissue replaces old with new tissue, there is an exception.
Following defect healing in bone e.g. after a fracture or the placement of a dental implant the new bone formed during this process is immediately remodeled and replaced.
The reason for this instant remodeling of new bone can be explained as follows: In the early stages of healing a biomechanically inferior type of bone (woven bone and plexiform bone) is synthesized very quickly to stabilize the defect area. After this has been achieved, remodeling of this provisional tissue is initiated at once and biomechanically more competent lamellar bone is formed at a slower pace.
In other words a temporary "emergency" solution is replaced via remodeling with a permanent one.
Stefan, bone tissue remodeling with resultant "new bone formation" is an excellent example of "new" tissue formation.
Dennis
Dennis Mazur
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