Reaction of dopamine with a ketone in DMF at 110 degree celsius, no product is observed. what could be the reason?

Reeba Susan Thomas @Reeba-Thomas-6

19 May 2025 1 5K Report

i did a reaction of dopamine with acetophenone in dmf using acetic acid as catalyst. But no product is formed.

James Demers

Effective methods in the attached paper. Curiously, they used base rather than acid catalysis.

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