How should I provide a 10mM PVP solution. Since PVP avg molecular weight is around 40,000m, it does not make sense to use the average molecular weight to calculate the required PVP mass for making a 10mM PVP solution. However, the PVP monomer has a molecular weight of 111.14 g/mol. Should I use the monomer molecular weight for making the 10mM PVP Solution?
Mina Karimi-Avargani
Dear Hamidreza Moazzeni,
For preparing polymer solution, the concentration is calculated according the molecular weight of polymer. PVP is a water-soluble polymer and for preparation 10mM solution, it is necessary to solve 400 g PVP in water which the final volume is 1000 mL.
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