There is inverse relationship between protein intake and risk of heart diseases because cholesterol start to increase as liver and cell process fats have low efficiently ( liver and other other cell required protein to its function)
Gut microbe–derived metabolites that are biologically active such as trimethylamine N-oxide (TMAO) are now recognized as contributors to atherogenesis and cardiovascular diseases. Choline-containing nutrients that reach the intestine and therefore the colon can act as "fuel" for the intestinal microbiota, with relative trimethylamine production (TMA). TMA is rapidly and further oxidized to trimethylamine-N-oxide (TMAO) from liver monooxygenases containing Flavina (FMO).For example, choline is present in red meats.
I think , protein is nutrient for growth and optimal health, therefore relation between heart disease and protein intake is inversely
Have a look at this useful link.
https://www.nature.com/articles/s42255-019-0162-4
Also, see the RG links below.
Article Intake of Different Dietary Proteins and Risk of Heart Failu...
Article High Protein Intake Associates with Cardiovascular Events bu...
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