Dear Community. I would like to ask you if somebody knows, of some cell line available to buy or request, that replicates in some way, the growing/survival results obtained with the real TIL culture. May I use peripheral blood Lymphocytes (PBL) as a model of TIL cells?. I mean, if PBL grows well, maybe is very likely that TIL cells will do likewise?
The idea behind this question is to ask you if you know some "Bio-tool" (cell line or eventually bio-markers) to evaluate the quality/efficacy of our PBMCs to grow TIL-cells. For example, the measurement of CD137L in the Feeder Cells could be a good idea?, IL-2 expression?. Anti CD3/CD28 activity?
Thanking you in advance!, best, Adrian
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