In an article titled, 'Mass drug administration for scabies' in three island communities in Fiji published in New England Journal of Medicine reported that oral ivermectin 1st dose for all and 2nd dose for infected patients led to a reduction in the prevalence of scabies 2 years after intervention by 89% but this reduction is only 59% in standard care group (Topical permethrin to the infected patients and their contacts). What might be the reasons behind these differences in prevalence?
Sarcoptes scabiei is the parasite that cause scabies. It burrows under the skin. It cause itchy skin and discomfort. Ivermectin taken orally, physiologically, is
Spread throughout the body. Its impact is holistically exerted on the parasite leading to its greater destruction than topical adminstration whose impact is partial and leads to a lesser destruction.
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