What is the role of nitric oxide in sickle cell disease management?
Dear nitric oxide increases the pain crisis noticed in sickle cell patients especially in crisis stage because the level of nitric oxide is elevated. In the management the level should be controlled.
these URLs articles explain nicely the role of nitric oxide
Article Sickle cell disease and nitric oxide: A paradigm shift?
http://www.bloodjournal.org/content/112/11/sci-48?sso-checked=true
https://www.eurekalert.org/pub_releases/2014-03/mcog-llo032014.php
Some useful links:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199240/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460398/
https://clinicaltrials.gov/ct2/show/NCT00009581
https://www.sciencedirect.com/science/art
Please have a look at this similar RG discussion thread.
https://www.researchgate.net/post/What_is_the_role_of_Nitric_Oxide_in_Sickle_Cell_disease_Management
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