Hello Research Gate Community!
I am teaching a class on immunology for a general cell biology course, pretty much following the immunology chapter in Alberts (chapter 24). I was confused about a figure think I may have found a mistake in figure 24-47 but wanted to check with the community since my immunology background is not particularly strong. In the attached figure 24-47, on the right it shows antigen presentation between the effector-T-cell and B-cell. As I understand it, and as described in the legend, B cells bind antigen via their BCR, internalize and proteolyze it and and present it on MHC class II, which is recognized by the TCR on the T-cell. In the picture, I think the TCR-Antigen-MHC-II complex is upside down. The TCR (in black) should be down, attached to the T-Cell, right? And the MHC-II (green) should be above, on the B-Cell, right? I want to make sure I understand the process well for the class and would also report this mistake to the publishers. Thanks for your help!