Is there a lower intensity (not dose) limit, below which, the UVC light has no effect on DNA?
If so, does anyone have a good reference on the matter?
It has been reported, that Far -UVC light at 207–222 nm wavelength range with an intensity of two mJ/cm2 may cause damage to microbial (viral/bacterial) DNA particularly flue causing viruses compared to the damage done to mammalian DNA. The researchers have reported that Far-UVC of 222 nm has a limited range of penetration which cannot penetrated through the dead keratinized human skin. Also the small size of viruses and bacteria renders them vulnerable to the penetration of the Far-UVC of 222 nm range. In mice it was observed that the Far UV at 222 damage the viral/bacterial DNA and not the mice DNA
https://www.genengnews.com/topics/translational-medicine/uv-light-that-is-safe-for-humans-but-bad-for-bacteria-and-viruses/
https://www.laserfocusworld.com/lasers-sources/article/16555364/uv-sterilization-faruvc-light-kills-airborne-flu-viruses-without-danger-to-humans
D. Welch et al., Sci. Rep. (2018); doi:10.1038/s41598-018-21058-w.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201259
Thank you Gladys. I was not aware of this work and I am quite surprised that such a low dose at 222nm have such an effect.
I am still in doubt whether there is a lower limit for the light intensity. The two mJ/cm2 could be applied with a high intensity for a short time or with a low intensity for a long time. The dose would be the same, but would the inactivation efficiency be the same as well?
it will depend on the distance of the device and the equipment that is to be treated !
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