Hello All

My question pertains to a strange situation in mediation analysis. Let us suppose my 1st hypothesis says A affects C. Then, my 2nd hypothesis says B mediates relationship of A and C.

If I find support for indirect effect for B (B indeed mediates), what happens to my 1st hypothesis? How do I interpret it? If the support is not found for 1st hypothesis then how do you define this case?

I have seen papers where they have merely reported that A does not cause C (if 1st hypothesis isnt supported) and then state that B mediates A--->C relationship (if 2nd hypothesis is supported).

Am conceptually not able to make sense of this. Does this mean that while A does not affect C (Since the relationship is nonsig.), it does affect C through B? Isnt this contradictory?

PS: I am talking about complimentary mediation here, where paths A to B, and B to C have the same sign coefficient.

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