A number of Text books of Pharmaceutics give information about microencapsulation of drugs for different reasons. The major objective of microencapsulation is to achieve sustained release of actives from delivery system. Moreover, microencapsulated systems are divided into two types, matrix type and reservoir type. I am confused that either these terminologies i.e matrix and reservir based are only applicable to sustained release products. OR we can consider conventional tablets (without any release retardant material) as matrix type delivery system and conventional capsules as reservoir based drug delivery system..??????????????
Matrix system and Reservoir system are not for conventional dosage form. These two system (Matrix and Reservoir) explores the modified or sustained or controlled release dosage form to have a patient compliance. In addition, to reduce the dosing frequency.
Thanks Pradum Pundlikrao lge for your response. OK, i agree with you. These terms are usually used for describing nature of sustained release products in pharmaceutical technology. In chapters of conventional dosage forms like tablets and capsules, these terms are rarely found.
A matrix system is one where the drug is dispersed in very small particles into a solid and homogeneous block of polymer or release-retardant substance. A reservoir system is one as a mycrocapsule, where a big particle of drug (or many agglomerated particles of drug) are covered by a polymer or other release- retardant material forming a wall through the drug must diffuse to be released. This is to avoid confusions between both systems.
I agree Muhammad, if you draw a diagrammatic representation of a tablet or capsule they do look like a matrix system and reservoir system respectively but as you understand these terms have been coined for controlled release products that use non-dissolving or slow-dissolving materials for the matrix/capsule while standard tablets and capsules are commonly referred to as immediate release dosage forms and these dissolve to release their active contents in minutes.
It can be used for any dosage form as long as the rate of drug release is similar
For more detail, please see first chapter of this book, it has detailed explanation
https://www.goodreads.com/en/book/show/2177078.Novel_Drug_Delivery_Systems
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