Hi Gudrun,

have you searched your question on " Google Scholar"  adn not Google.

If not try it .

give your question :

MALDI-TOF MS in clinical pathology for somatic mutation testing?

in the Google Scholar  mask:

you ´' earn ca. 4200 hits.

Here the link:

https://scholar.google.de/scholar?hl=de&q=MALDI-TOF+MS+in+clinical+pathology+for+somatic+mutation+testing%3F+&btnG=&lr=

Best Regards

JRG

Thank you for the hint.

The intention to implement such an instrument for mutation testing lasted only short at my institute. Now they try to build up NGS. Maybe I have a look for my personal interest.

bye and thanks again.

Hi Gudrun,

Bruker has an FDA approval of the use of MALDI Biotyper CA  for the indentation of Gram negative bacterial colonies cultured from human specimens.

That si by my knowledge the only clinical application of MALDI so far.

Here is a link to the FDA decision

http://www.accessdata.fda.gov/cdrh_docs/reviews/K130831.pdf

Best,

Ivan

P.S. The idea of mutation testing is quite interesting,though.